• Microbiology

    The metal matters

    Life on earth is carbon-based, but carbon-based life is impossible without metals. All living organisms, without exception, need metals to live. And so, all organisms must carefully manage their metal nutrition. They must find and take up enough metals, store metals if necessary, and apportion metals correctly to different organs, cells, organelles, and finally to specific proteins and enzymes. And, to avoid having too much of a good thing, all living organisms must also dispose of any surplus metal. The question is how? I have devoted my academic career to studying one metal, namely copper. Like the more familiar metals…

  • Microbiology - Space science

    Space flight technology benefiting human health

    Using space technology right here on Earth. When individual human cells were cultured in the microgravity environment of spaceflight in the 1990s, scientists noticed that they started to aggregate and organize as structures that resembled the native tissue from which the cells were derived. This was very different to cells grown under normal gravity conditions, that sediment to the bottom of the culture dish, precluding tissue development. This finding triggered great interest by tissue engineers, and resulted in the use of the microgravity research platform to engineering tissue-like or organotypic models (1). Based on this principle, NASA engineers have developed…